The General Hospital spoilers video preview for September 21-25 focuses on a secret at risk of being outed. Sonny and Justine have been keeping their relationship hidden for months. That time may be over. Meanwhile, is Ava about to be truthful or double down on deception? And there’s high-stakes drama unfolding at the prison. Curtis has the opportunity to come to Sidwell’s rescue. Will he take it?
Key Takeaways
- Ava considers revealing what she knows about the person framing Nina.
- Sonny and Justine’s secret relationship may finally be exposed.
- Curtis faces a difficult choice when Sidwell lands in danger at Pentonville.
This Week on General Hospital: September 21-25, 2026
Will Ava Come Clean to Willow?
Ava (Maura West) is dealing with a dilemma. And even though she is an expert at self-preservation, her bestie, Nina (Cynthia Watros), is in real trouble. This week, she talks to Willow (Katelyn MacMullen). “Nina is being framed. I may know by whom.”
Willow already has to suspect that Drew (Cameron Mathison) is the one who framed her mother. There’s no way Ava would confirm those suspicions, right? Ava must tread lightly here. If Drew goes down, she goes down. And she’s not going to let that happen. She has Avery to think about.
Somebody May Find Out About Justine and Sonny
Next up: Justine (Nazneen Contractor) and Sonny (Maurice Benard). Just as we see a close, public moment between them, we hear Justine say, “Our secret’s out.” Sonny wouldn’t really have a problem with this. Now that he’s going legit, he would love for the world to know about them. It’s Justine who wants to keep things quiet because she plans to run for the open district attorney seat.

The question here is whether the person who spies Justine and Sonny will do anything with this information. For example, if it were Drew, then Justine and Sonny would have plenty to worry about.
Sonny will have more issues to handle. When somebody says, “He has to go down,” Sonny tells Ric (Rick Hearst), “Let them try.” This could be about Ava and Drew and their plan to make Sonny pay.
Roommate Drama at Pentonville
Finally, it looks like Sidwell (Carlo Rota) will be in trouble, and Curtis (Donnnell Turner) is in the middle of it. “Find a reason not to be in your cell after lunch,” he is warned as Sidwell is surrounded by fellow inmates. Will Curtis come to his cellmate’s rescue?
